Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL2330089

COc1ccc2ccc(S(=O)(=O)N[C@H]3CCN(Cc4ccc(C(=N)N)cc4)C3=O)cc2c1.O=C(O)C(F)(F)F

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.88
F2 P00734 7/20 0.74
PLG P00747 2/20 0.74
PROC P04070 2/20 0.74
PRSS1 P07477 2/20 0.74
PLAT P00750 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL2328672 0.92 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2329113 0.92 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2329417 0.91 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2334128 0.91 F10 (0.73) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2331936 0.88 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2331932 0.88 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2335620 0.88 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2335622 0.88 F10 (0.89) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2329452 0.87 F10 (0.80) F10F2PLGPROCPRSS1
Trifluoroacetic Acid SCHEMBL2329514 0.87 F10 (0.92) F10F2PLGPROCPRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853618-B1 SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMA INC (US) 2011-08-17 EP disclosed