Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 8/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL848262 | 0.78 | MAPT (0.44) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL13137279 | 0.75 | MAPT (0.44) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL12113060 | 0.75 | MAPT (0.44) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL5151856 | 0.75 | MAPT (0.61) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL12110242 | 0.74 | CDK1 (0.41) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL2954134 | 0.72 | IDO1 (0.36) | — | |
| SCHEMBL5151850 | 0.71 | MAPT (0.56) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL30450069 | 0.71 | EGLN1 (0.44) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL30449735 | 0.70 | EGLN1 (0.46) | MAPTKDM4EALDH1A1APEX1RECQL | |
| SCHEMBL30449897 | 0.68 | EGLN1 (0.39) | MAPTKDM4EALDH1A1APEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021084765-A1 | 4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD (JP) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021085653-A1 | 4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2021-05-06 | — | — | WO | disclosed |