⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571403 | 0.81 | TSHR (0.38) | — | |
| SCHEMBL1741550 | 0.76 | — | — | |
| SCHEMBL233378 | 0.74 | — | — | |
| SCHEMBL5169567 | 0.72 | — | — | |
| SCHEMBL56357 | 0.72 | — | — | |
| SCHEMBL2120614 | 0.71 | — | — | |
| SCHEMBL8806187 | 0.70 | — | — | |
| SCHEMBL59533 | 0.70 | HMGCR (0.41) | — | |
| SCHEMBL4169864 | 0.70 | HMGCR (0.45) | — | |
| SCHEMBL4429121 | 0.70 | HMGCR (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 537 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037329-B2 | SphK inhibitors and methods of making and using same | WASHINGTON UNIVERSITY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240226342-A1 | REACTIVE OXYGEN SPECIES IMAGING AGENTS | WASHINGTON UNIVERSITY (US) | 2024-07-11 | — | — | US | disclosed |
| CN-113677364-B | Pharmaceutical compositions comprising anti-191P 4D12 antibody drug conjugates and methods of use thereof | 艾更斯司股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2024133845-A1 | CONJUGATES COMPRISING A PHOSPHORUS(V) MOIETY AND A DRUG | TUBULIS GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-12016842-B2 | Methods of using anti-CD79b immunoconjugates | GENENTECH, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20240190958-A1 | NOVEL ANTIBODY DRUG CONJUGATES WITH NOVEL NAPI2B ANTIBODIES, THERAPEUTIC METHODS AND USES THEREOF | TUBULIS GMBH (DE) | 2024-06-13 | — | — | US | disclosed |
| EP-4380978-A1 | METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA | Genentech, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| EP-4378482-A2 | DOSING REGIMENS FOR ANTI-CD30 VC-PAB-MMAE ANTIBODY DRUG-CONJUGATES | Seagen Inc. (US) | 2024-06-05 | — | — | EP | disclosed |
| US-20240179825-A1 | SYSTEMS AND METHODS FOR NONEQUILIBRIUM PLASMAS | WASHINGTON UNIVERSITY | 2024-05-30 | — | — | US | disclosed |
| US-20240167096-A1 | PLASMA CELL-FREE RNA AND METHODS OF USE THEREOF AS NON-INVASIVE BIOMARKERS FOR ALZHEIMER'S DISEASE | WASHINGTON UNIVERSITY (US) | 2024-05-23 | — | — | US | disclosed |
| US-20050014727-A1 | Diphenylethylene compounds and uses thereof | CELGENE CORPORATION | 2005-01-20 | — | — | US | disclosed |
| EP-1476141-A2 | TAMPER-RESISTANT TRANSDERMAL OPIOID DELIVERY DEVICES | Euro-Celtique, S.A. (LU) | 2004-11-17 | — | — | EP | disclosed |
| WO-2004078144-A2 | DIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CELGENE CORPORATION (US) | 2004-09-16 | — | — | WO | disclosed |
| WO-2004052282-A2 | DITERPENOID COMPOUNDS, COMPOSITIONS THEREOF AND THEIR USE AS ANTI-CANCER OR ANTI-FUNGAL AGENTS | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2004-06-24 | — | — | WO | disclosed |
| US-20040044003-A1 | Therapeutic agents useful for treating pain | PURDUE PHARMA L.P. | 2004-03-04 | — | — | US | disclosed |
| US-20040033253-A1 | Acyl opioid antagonists | PURDUE PHARMA L.P. | 2004-02-19 | — | — | US | disclosed |
| WO-2004010957-A2 | DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE | SEATTLE GENETICS, INC. (US) | 2004-02-05 | — | — | WO | disclosed |
| WO-2004002983-A2 | THERAPEUTIC PIPERAZINE DERIVATIVES USEFUL FOR TREATING PAIN | EURO-CELTIQUE, S.A. (LU) | 2004-01-08 | — | — | WO | disclosed |
| US-20040006091-A1 | Therapeutic agents useful for treating or preventing pain | PURDUE PHARMA L.P. | 2004-01-08 | — | — | US | disclosed |
| WO-2003070191-A2 | TAMPER-RESISTANT TRANSDERMAL OPIOID DELIVERY DEVICES | EURO-CELTIQUE, S.A. (LU) | 2003-08-28 | — | — | WO | disclosed |