Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.68 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.68 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51920 | 0.87 | S1PR5 (0.81) | S1PR5S1PR1FUCA1 | |
| SCHEMBL565212 | 0.87 | S1PR5 (0.87) | S1PR5S1PR1FUCA1 | |
| SCHEMBL29032382 | 0.86 | S1PR5 (0.63) | S1PR5S1PR1KDM4EALDH1A1HPGD | |
| SCHEMBL3440339 | 0.86 | S1PR5 (0.63) | S1PR5S1PR1KDM4EALDH1A1HPGD | |
| SCHEMBL3063205 | 0.84 | KDM4E (0.69) | KDM4EALDH1A1HPGDCYP2D6MEN1 | |
| SCHEMBL23182612 | 0.84 | S1PR5 (0.66) | S1PR5S1PR1FUCA1KDM4EALDH1A1 | |
| SCHEMBL1792829 | 0.84 | S1PR5 (0.66) | S1PR5S1PR1FUCA1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4505675 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1HPGDCYP2D6MEN1 | |
| SCHEMBL3290324 | 0.82 | MEN1 (0.68) | SIGMAR1MEN1TSHRKMT2A | |
| SCHEMBL1438433 | 0.82 | S1PR5 (0.72) | S1PR5S1PR1FUCA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023212612-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN SHAWN (US) | 2023-11-02 | — | — | WO | disclosed |
| EP-2534151-A1 | 8-METHYL-1-PHENYL-IMIDAZOL[1,5-A]PYRAZINE COMPOUNDS | MSD Oss B.V. (NL) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011095556-A1 | 8-METHYL-1-PHENYL-IMIDAZOL[1,5-A]PYRAZINE COMPOUNDS | N.V. ORGANON (NL) | 2011-08-11 | — | — | WO | disclosed |