Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 6/20 | 0.45 |
| ▸ | NAMPT | P43490 | 5/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22098106 | 0.82 | NOTUM (0.47) | NAMPTHDAC1ABHD6 | |
| SCHEMBL30838602 | 0.82 | HDAC1 (0.47) | NAMPTHDAC1ABHD6 | |
| SCHEMBL29710237 | 0.81 | MAPT (0.47) | NAMPTHDAC1ABHD6 | |
| SCHEMBL17034782 | 0.81 | NAMPT (0.48) | NAMPTHDAC1 | |
| SCHEMBL8228976 | 0.81 | MAPT (0.47) | NAMPTHDAC1ABHD6 | |
| SCHEMBL29379757 | 0.80 | HDAC1 (0.46) | NAMPTHDAC1ABHD6 | |
| SCHEMBL1721216 | 0.80 | HDAC1 (0.46) | NAMPTHDAC1ABHD6 | |
| SCHEMBL4753742 | 0.79 | HDAC1 (0.48) | NAMPTHDAC1ABHD6 | |
| SCHEMBL17037044 | 0.78 | NAMPT (0.51) | NAMPTHDAC1 | |
| SCHEMBL17106486 | 0.78 | NAMPT (0.46) | NAMPTHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365192-B2 | Pyridine compound substituted with azole | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-21 | — | — | US | disclosed |
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | CYP2C19, CYP4A11, CYP11B1 | RIPK1 3654/4885NAMPT 659/4885HDAC1 675/4885 |
| US-11365192-B2 | Pyridine compound substituted with azole | CYP2C19, CYP4A11, CYP11B1 | RIPK1 3654/4885NAMPT 659/4885HDAC1 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.