Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 15/20 | 0.51 |
| ▸ | JAK2 | O60674 | 2/20 | 0.48 |
| ▸ | JAK1 | P23458 | 2/20 | 0.48 |
| ▸ | TYK2 | P29597 | 2/20 | 0.48 |
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | CD69 | Q07108 | 3/20 | 0.47 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24807690 | 0.94 | BTK (0.50) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23276995 | 0.89 | BTK (0.51) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL24807680 | 0.89 | JAK2 (0.52) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23276927 | 0.89 | JAK2 (0.52) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23276746 | 0.87 | JAK2 (0.50) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23276817 | 0.86 | JAK1 (0.57) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23312193 | 0.86 | JAK2 (0.51) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL24806499 | 0.85 | JAK2 (0.54) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23312125 | 0.85 | JAK2 (0.48) | BTKJAK2JAK1TYK2JAK3 | |
| SCHEMBL23276656 | 0.85 | BTK (0.51) | BTKJAK2JAK1TYK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078022-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |