Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.96 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701863 | 1.00 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7856315 | 1.00 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL30701864 | 1.00 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7856311 | 1.00 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7854826 | 1.00 | POLB (0.96) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7006523 | 0.98 | POLB (1.00) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL7854448 | 0.94 | POLB (0.92) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL6753973 | 0.91 | POLB (0.80) | POLBNPC1RAB9ADDAH1PDE10A | |
| SCHEMBL8150863 | 0.91 | POLB (0.80) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL21074131 | 0.91 | POLB (0.80) | POLBNPC1RAB9ADDAH1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098829-A1 | NUCLEIC ACID COMPLEXES | PROCARTA BIOSYSTEMS LTD (GB) | 2011-08-18 | — | — | WO | disclosed |