Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.36 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20210254 | 0.74 | TSHR (0.42) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28478763 | 0.72 | NPSR1 (0.50) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL15655480 | 0.72 | MEN1 (0.59) | NUDT1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL18009822 | 0.72 | ADORA2A (0.40) | NUDT1ADORA2AADORA1ALDH1A1KDM4E | |
| SCHEMBL31396067 | 0.72 | KDM4E (0.52) | ALDH1A1KDM4EHPGDLMNATP53 | |
| SCHEMBL20748444 | 0.72 | ADORA2A (0.42) | NUDT1ADORA2AADORA1TTBK1TTBK2 | |
| SCHEMBL18572717 | 0.72 | NPSR1 (0.60) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9912500 | 0.72 | PIK3CA (0.50) | NUDT1ADORA2AADORA1TTBK1TTBK2 | |
| SCHEMBL5134352 | 0.71 | ADORA2A (0.44) | NUDT1ADORA2AADORA1KMT2AALDH1A1 | |
| SCHEMBL25781781 | 0.71 | ADORA2A (0.40) | NUDT1ADORA2AADORA1CDK8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |