Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 6/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.67 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.67 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710907 | 0.85 | FGFR1 (0.49) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL27218134 | 0.81 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL16071554 | 0.79 | FGFR2 (0.49) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL15412886 | 0.79 | FGFR4 (0.70) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL15413227 | 0.78 | FGFR4 (0.69) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL24225265 | 0.76 | FGFR4 (0.66) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL1983011 | 0.76 | PLK2 (0.56) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL16245982 | 0.76 | FGFR1 (0.49) | FGFR1 | |
| SCHEMBL20734021 | 0.75 | FGFR1 (0.40) | FGFR4FGFR1FGFR2FGFR3EGFR | |
| SCHEMBL13553975 | 0.75 | WEE1 (0.38) | FGFR4FGFR1FGFR2FGFR3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2872491-B1 | INHIBITORS OF THE FIBROBLAST GROWTH FACTOR RECEPTOR | BLUEPRINT MEDICINES CORP (US) | 2021-05-05 | — | — | EP | disclosed |