Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.70 |
| ▸ | CASP2 | P42575 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 2/20 | 0.57 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19468480 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL19468499 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL1694195 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL2449717 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL35191 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL2442650 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL2443838 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL19468510 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL17979588 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL19468468 | 1.00 | EPHX1 (0.70) | EPHX1CASP2NAAAZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996905-A | Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases | 生物药品解决方案有限公司 | 2023-04-21 | — | — | CN | claimed |
| CN-110483369-B | Method for synthesizing (7S) -5-azaspiro [2.4] heptane-7-radical carbamic acid tert-butyl ester | 广州康瑞泰药业有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-111419830-A | Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes | 比皮艾思药物研发有限公司 | 2020-07-17 | — | — | CN | claimed |
| CN-110483369-A | The method for synthesizing (7S) -5- azaspiro [2.4] heptane -7- carbamate | CHEM STONE INC | 2019-11-22 | — | — | CN | claimed |
| CN-105906545-B | A kind of preparation method for synthesizing sitafloxacin intermediate (7S) -5- azaspiros [2.4] heptane -7- carbamates | 广州康瑞泰药业有限公司 | 2018-06-29 | — | — | CN | claimed |
| CN-105906545-A | Preparation method for efficiently synthesizing Sitafloxacin midbody (7S)-5-azaspiro[2.4] heptanes-7-phenylbutane | 广州康瑞泰药业有限公司 | 2016-08-31 | — | — | CN | claimed |
| EP-1309575-B1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2005-06-08 | — | — | EP | claimed |
| EP-1309575-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | Galderma Research & Development (FR) | 2003-05-14 | — | — | EP | claimed |
| WO-2002012210-A9 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RES & DEV (FR) | 2002-04-18 | — | — | WO | claimed |
| WO-2002012210-A1 | BIPHENYL DERIVATIVES AND THEIR USE AS PPAR-GAMMA RECEPTOR ACTIVATORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2002-02-14 | — | — | WO | claimed |
| US-6323196-B1 | ENZYME INHIBITORS AND COGNITION ACTIVATORS | AVENTIS PHARMACEUTICALS INC. | 2001-11-27 | — | — | US | claimed |
| EP-1020469-A2 | Galanthamine derivatives, a process for their preparation and their use as medicaments | SYNAPTECH, INC. (US) | 2000-07-19 | — | — | EP | claimed |
| EP-0571434-B1 | A PROCESS FOR THE PREPARATION OF 1,3a,8-TRIMETHYL-1,2,3,3a,8,8a-HEXAHYDRO-PYRROLE 2,3-b]INDOL-5(3aS,8aR)-HEPTYLCARBAMATE | LABORATORIO CHIMICO INT SPA (IT) | 1995-08-02 | — | — | EP | claimed |
| EP-0648771-A1 | Galanthamine derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1995-04-19 | — | — | EP | claimed |
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | claimed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | claimed |
| EP-0154864-B1 | PHYSOSTIGMINE DERIVATIVES WITH ACETYLCHOLINESTERASE INHIBITION PROPERTIES, AND THE RELATIVE PRODUCTION PROCESS | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-07-25 | — | — | EP | claimed |
| CN-118382612-A | Method for producing blocked isocyanate compound and method for producing isocyanate compound | 旭化成株式会社 | 2024-07-23 | — | — | CN | disclosed |
| EP-0055359-B1 | PROCESS FOR THE PREPARATION OF 1-ALKENYL ISOCYANATES | BASF Aktiengesellschaft (DE) | 1983-08-24 | — | — | EP | disclosed |
| EP-0055359-A1 | Process for the preparation of 1-alkenyl isocyanates | BASF Aktiengesellschaft (DE) | 1982-07-07 | — | — | EP | disclosed |