Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584039 | 0.84 | — | — | |
| SCHEMBL6245189 | 0.84 | PHGDH (0.56) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL6664812 | 0.84 | PHGDH (0.56) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL24302231 | 0.84 | PHGDH (0.56) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL5784736 | 0.84 | PHGDH (0.56) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL12424247 | 0.81 | FYN (0.37) | ALDH1A1 | |
| SCHEMBL13943568 | 0.81 | PHGDH (0.54) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL8346650 | 0.81 | PHGDH (0.54) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL13942560 | 0.81 | PHGDH (0.52) | PHGDHMGLLMEN1KMT2APOLB | |
| SCHEMBL19034085 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3517536-B1 | AMINOTRIAZINE DERIVATIVES USEFUL AS TANK-BINDING KINASE INHIBITOR COMPOUNDS | GILEAD SCIENCES INC (US) | 2021-05-05 | — | — | EP | disclosed |