Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23316776 | 0.93 | HPGD (0.44) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542235 | 0.89 | HPGD (0.46) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542200 | 0.88 | HPGD (0.47) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542206 | 0.88 | HPGD (0.47) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542184 | 0.88 | HPGD (0.45) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542236 | 0.87 | NPC1 (0.52) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23316791 | 0.86 | KDM4E (0.38) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542195 | 0.85 | HPGD (0.44) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542226 | 0.83 | HPGD (0.47) | HPGDKDM4EALDH1A1RAB9AGAA | |
| SCHEMBL23542252 | 0.83 | HPGD (0.47) | HPGDKDM4EALDH1A1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3583100-B1 | COMPOUNDS CONTAINING SI ATOMS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-05-05 | — | — | EP | disclosed |