Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20469259 | 0.84 | — | — | |
| SCHEMBL12515879 | 0.84 | HMGCR (0.34) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL21371133 | 0.81 | HMGCR (0.38) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL826204 | 0.79 | — | — | |
| SCHEMBL18117573 | 0.78 | TSHR (0.39) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL18941948 | 0.76 | — | — | |
| SCHEMBL19537646 | 0.73 | — | — | |
| SCHEMBL22872160 | 0.72 | NAALAD2 (0.36) | TSHRHIF1A | |
| SCHEMBL18751328 | 0.71 | HMGCR (0.44) | HMGCRCHRM1TBXA2RADRA1AFFAR1 | |
| SCHEMBL2710379 | 0.70 | HMGCR (0.42) | HMGCRCHRM1TBXA2RADRA1AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3576717-B1 | NANOPARTICLE-BASED LIVER-TARGETING THERAPY | MIDATECH LTD (GB) | 2021-05-05 | — | — | EP | disclosed |