Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21337669 | 0.91 | ADORA1 (0.35) | ADORA3ADORA2AADORA2BADORA1PIK3CD | |
| SCHEMBL19917142 | 0.80 | EGFR (0.44) | ADORA3ADORA2AADORA1 | |
| SCHEMBL23316958 | 0.77 | — | — | |
| SCHEMBL20112029 | 0.67 | P2RY12 (0.32) | ADORA3ADORA2AADORA2BADORA1P2RY12 | |
| SCHEMBL19489658 | 0.66 | KMT5B (0.31) | — | |
| SCHEMBL21230671 | 0.66 | HPGD (0.30) | — | |
| SCHEMBL21397245 | 0.66 | PDE8B (0.34) | P2RY12 | |
| SCHEMBL19250314 | 0.65 | P2RY12 (0.33) | P2RY12 | |
| SCHEMBL22243284 | 0.64 | EGFR (0.47) | ADORA1PIK3CD | |
| SCHEMBL19917141 | 0.64 | KMT2A (0.41) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356348-B1 | 2-AMINOQUINAZOLINE DERIVATIVES AS P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LTD (GB) | 2021-05-05 | — | — | EP | disclosed |