Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 9/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2331690 | 1.00 | CHKA (0.76) | CHKA | |
| Bromide SCHEMBL14739897 | 1.00 | CHKA (0.76) | CHKA | |
| Water SCHEMBL2337012 | 0.99 | CHKA (0.74) | CHKA | |
| Water SCHEMBL2337015 | 0.99 | CHKA (0.74) | CHKA | |
| Water SCHEMBL14740255 | 0.89 | CHKA (0.88) | CHKA | |
| Water SCHEMBL2332936 | 0.85 | CHKA (0.80) | CHKA | |
| Water SCHEMBL2550773 | 0.85 | CHKA (0.97) | CHKA | |
| Water SCHEMBL14740004 | 0.85 | CHKA (0.97) | CHKA | |
| SCHEMBL2328461 | 0.84 | CHKA (0.97) | CHKA | |
| SCHEMBL2550131 | 0.84 | CHKA (0.97) | CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533815-A1 | NUCLEIC ACID COMPLEXES | Procarta Biosystems Ltd (GB) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011121357-A2 | TRANSCRIPTION FACTOR DECOYS | PROCARTA BIOSYSTEMS LIMITED (GB) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011098829-A1 | NUCLEIC ACID COMPLEXES | PROCARTA BIOSYSTEMS LTD (GB) | 2011-08-18 | — | — | WO | disclosed |