Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21133845 | 0.88 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL20445802 | 0.86 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL23316973 | 0.84 | RPS6KB1 (0.81) | RPS6KB1 | |
| SCHEMBL23316983 | 0.83 | RPS6KB1 (0.80) | RPS6KB1 | |
| SCHEMBL23316787 | 0.82 | RPS6KB1 (0.81) | RPS6KB1 | |
| SCHEMBL23316966 | 0.81 | RPS6KB1 (0.80) | RPS6KB1 | |
| SCHEMBL20445821 | 0.80 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL20445822 | 0.80 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL20593864 | 0.80 | RPS6KB1 (1.00) | RPS6KB1 | |
| SCHEMBL20593775 | 0.80 | RPS6KB1 (1.00) | RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356348-B1 | 2-AMINOQUINAZOLINE DERIVATIVES AS P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LTD (GB) | 2021-05-05 | — | — | EP | disclosed |