Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | OTC | P00480 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17027585 | 0.77 | KDM4E (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL6700217 | 0.75 | KDM4E (0.56) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL2064554 | 0.73 | KDM4E (0.53) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL1562522 | 0.71 | KDM4E (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL5968120 | 0.71 | KDM4E (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL7825106 | 0.71 | KDM4E (0.50) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL27610980 | 0.71 | — | — | |
| Medronic Acid SCHEMBL66716 | 0.69 | — | — | |
| Medronic Acid SCHEMBL8350837 | 0.69 | KDM4E (1.00) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL10861338 | 0.69 | KDM4E (0.47) | KDM4EMMP2THRBMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358398-A2 | OLIGOMERIC COMPOUNDS AND METHODS | Isis Pharmaceuticals, Inc. (US) | 2011-08-24 | — | — | EP | claimed |
| WO-2010048585-A2 | OLIGOMERIC COMPOUNDS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2010-04-29 | — | — | WO | claimed |
| WO-2011139911-A2 | LIPID FORMULATED SINGLE STRANDED RNA | ISIS PHARMACEUTICALS, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-4478763-A | TREATMENT OF DIPHOSPHONATE ESTERS WITH POTASSIUM TERT-BUTOXIDE AND PERCHLORYL FLUORIDE | UNIV. OF SOUTHERN CALIFORNIA (US) | 1984-10-23 | — | — | US | disclosed |