Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14702263 | 0.89 | CYP2D6 (0.36) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL14703062 | 0.89 | CYP2D6 (0.36) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL10089371 | 0.85 | CYP1A2 (0.39) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL15697799 | 0.85 | HPGD (0.39) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL10089343 | 0.84 | EGFR (0.37) | CYP2D6NR1I2LMNAADRA2AACHE | |
| Hydrochloric Acid SCHEMBL15675108 | 0.84 | HPGD (0.38) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL17500164 | 0.84 | PTGS1 (0.43) | LMNAPPARGPPARACYP2C19CYP2C9 | |
| SCHEMBL10089349 | 0.83 | AKR1C3 (0.34) | CYP2D6NR1I2LMNAADRA2AACHE | |
| SCHEMBL17500077 | 0.82 | HSP90AA1 (0.49) | CYP2D6PPARGPPARACYP2C19CYP2C9 | |
| SCHEMBL10089390 | 0.81 | AKR1C3 (0.35) | CYP2D6NR1I2LMNAADRA2AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2359930-A1 | A polymer prepared in the presence of metal complexes bearing a polydentate heteroatom ligand | Dow Global Technologies LLC (US) | 2011-08-24 | — | — | EP | disclosed |
| EP-1973655-A2 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-10-01 | — | — | EP | disclosed |
| WO-2007075299-A2 | POLYDENTATE HETEROATOM LIGAND CONTAINING METAL COMPLEXES, CATALYSTS AND METHODS OF MAKING AND USING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-07-05 | — | — | WO | disclosed |