SCHEMBL2331865

SCHEMBL2331865

C[Si](C)(C)OC=C(OCCl)OCCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4963502 0.65
SCHEMBL17635915 0.65
SCHEMBL28134575 0.65
SCHEMBL3089023 0.62
SCHEMBL3089026 0.62
SCHEMBL160478 0.62
SCHEMBL3077174 0.62
SCHEMBL11304750 0.60
SCHEMBL11304746 0.60
SCHEMBL11357920 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011098985-A1 METHOD FOR PREPARING ADAMANTYL COMPOUNDS FINORGA (FR) 2011-08-18 WO disclosed
WO-2010032129-A1 METHOD FOR PRODUCING ADAMANTYL COMPOUNDS FINORGA (FR) 2010-03-25 WO disclosed
EP-1581487-A4 METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF BRISTOL MYERS SQUIBB CO (US) 2007-08-08 EP disclosed
EP-1737970-A2 PROCESS FOR PREPARING DIPEPTIDYL IV INHIBITORS AND INTERMEDIATES THEREFOR Bristol-Myers Squibb Company (US) 2007-01-03 EP disclosed
WO-2005106011-A2 PROCESS FOR PREPARING DIPEPTIDYL IV INHIBITORS AND INTERMEDIATES THEREFOR BRISTOL-MYERS SQUIBB COMPANY (US) 2005-11-10 WO disclosed
EP-1581487-A2 METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF Bristol-Myers Squibb Company (US) 2005-10-05 EP disclosed
WO-2004052850-A2 METHODS AND COMPOUNDS PRODUCING DIPEPTIDYL PEPTIDASE IV INHIBITORS AND INTERMEDIATES THEREOF BRISTOL-MYERS SQUIBB COMPANY (US) 2004-06-24 WO disclosed