Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL2331986

N.O=S(=O)(Oc1ccccc1)C(F)(F)F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.54
CA2 P00918 6/20 0.54
CA9 Q16790 5/20 0.54
KMT2A Q03164 2/20 0.47
LMNA P02545 1/20 0.44
PPARG P37231 1/20 0.44
NFE2L2 Q16236 1/20 0.44
CXCR2 P25025 2/20 0.42
MEN1 O00255 1/20 0.42
CXCR1 P25024 1/20 0.41
CA5A P35218 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
DRD2 P14416 1/20 0.38
DRD1 P21728 1/20 0.38
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8821206 0.98 CA1 (0.56) CA1CA2CA9KMT2ALMNA
SCHEMBL780030 0.98 CA1 (0.56) CA1CA2CA9KMT2ALMNA
SCHEMBL1128833 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
SCHEMBL28043817 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
SCHEMBL27804335 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
Methane SCHEMBL27573607 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
SCHEMBL6923665 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
SCHEMBL28807949 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
Iodide SCHEMBL3347577 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA
Hydrogen Sulfide SCHEMBL6734260 0.95 CA1 (0.54) CA1CA2CA9KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8002851-B2 Thermochromic ink and coating compositions NBCUNIVERSAL MEDIA LLC (US) 2011-08-23 US disclosed
US-20100234504-A1 THERMOCHROMIC INK AND COATING COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2010-09-16 US disclosed