Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27532988 | 0.85 | CYP19A1 (0.55) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL5828718 | 0.84 | CYP19A1 (0.54) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL6257538 | 0.84 | CYP19A1 (0.54) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL10430003 | 0.84 | CYP19A1 (0.48) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL7807147 | 0.81 | KDM4E (0.55) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL6597520 | 0.81 | CYP19A1 (0.51) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL10583924 | 0.80 | CYP19A1 (0.50) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL8116597 | 0.80 | CYP19A1 (0.50) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL28007741 | 0.80 | CYP19A1 (0.54) | CYP19A1MAPTNOS1POLBMAOB | |
| SCHEMBL7137674 | 0.80 | CYP19A1 (0.50) | CYP19A1MAPTNOS1POLBMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3818053-A1 | FUSED RING COMPOUND HAVING UREA STRUCTURE | Sanford Burnham Prebys Medical Discovery Institute (US) | 2021-05-12 | — | — | EP | disclosed |