SCHEMBL2332226

SCHEMBL2332226

CC(C)(P)C(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234200 0.70
SCHEMBL8780725 0.67
SCHEMBL1276874 0.67
SCHEMBL3123264 0.67
SCHEMBL7954975 0.67
Ammonia Solution, Strong SCHEMBL28456690 0.67
SCHEMBL1778620 0.65
SCHEMBL14942610 0.64
SCHEMBL8674649 0.64
SCHEMBL48368 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230348356-A1 BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION EVONIK OPERATIONS GMBH (DE) 2023-11-02 US disclosed
CN-110156837-B Propyl-bridged diphosphine ligands for alkoxycarbonyl 赢创运营有限公司 2023-05-23 CN disclosed
CN-113845545-A Butyl-bridged diphosphine ligands for alkoxycarbonylation 赢创运营有限公司 2021-12-28 CN disclosed
US-20210276939-A1 BUTYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION EVONIK OPERATIONS GMBH (DE) 2021-09-09 US disclosed
US-11028110-B2 Process for the alkoxycarbonylation of alcohols EVONIK OPERATIONS GMBH (DE) 2021-06-08 US disclosed
CN-107628948-B Process for the alkoxycarbonylation of alcohols 赢创运营有限公司 2021-04-20 CN disclosed
CN-110240616-B Tribiaryl monophosphine ligands, methods for their preparation and use in catalytic coupling reactions 东莞市均成高新材料有限公司 2021-03-23 CN disclosed
CN-107629092-B 1, 1' -bis (phosphino) ferrocene ligands for alkoxycarbonylation 赢创运营有限公司 2020-12-15 CN disclosed
CN-106632476-B Monophosphine compounds and palladium catalysts based thereon for the alkoxycarbonylation of ethylenically unsaturated compounds 赢创运营有限公司 2020-11-20 CN disclosed
EP-3527576-B1 PROPYL-BRIDGED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION EVONIK OPERATIONS GMBH (DE) 2020-11-18 EP disclosed
US-20060128959-A1 Process for the preparation of acylphosphines, acyl oxides and acyl sulfides IGM GROUP B.V. (NL) 2006-06-15 US disclosed
US-20050228190-A1 C1-symmetric bisphosphine ligands and their use in the asymmetric synthesis of pregabalin BAO JIAN 2005-10-13 US disclosed
WO-2005087370-A1 C1-SYMMETRIC BISPHOSPHINE LIGANDS AND THEIR USE IN THE ASYMMETRIC SYNTHESIS OF PREGABALIN WARNER-LAMBERT COMPANY LLC (US) 2005-09-22 WO disclosed
US-6888031-B1 Process for the preparation of acylphosphines, acyl oxides and acyl sulfides CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-05-03 US disclosed
US-20050054854-A1 Method for the production of arylamines MERCK PATENT GMBH (DE) 2005-03-10 US disclosed
CN-1582270-A Method for the production of arylamines COVION ORGANIC SEMICONDUCTORS (DE) 2005-02-16 CN disclosed
US-20040248855-A1 Process for the preparation of acylphosphines, acyl oxides and acyl sulfides IGM GROUP B.V. (NL) 2004-12-09 US disclosed
EP-1135399-B1 PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES CIBA SC HOLDING AG (CH) 2002-08-07 EP disclosed
EP-1135399-A1 PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES Ciba SC Holding AG (CH) 2001-09-26 EP disclosed
WO-2000032612-A1 PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-06-08 WO disclosed