SCHEMBL2332398

SCHEMBL2332398

CC1OC(c2ccc(C(F)(F)F)cc2)c2c1nc1c(c2C2CCN(C(=O)O)CC2)[C@@H](O)CC(C)(C)C1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL972744 0.88 CETP (0.70) CETP
SCHEMBL12444130 0.88 CETP (0.63) CETP
SCHEMBL12444148 0.87 CETP (0.64) CETP
SCHEMBL12921480 0.87 CETP (0.64) CETP
SCHEMBL973364 0.86 CETP (0.63) CETP
SCHEMBL972742 0.85 CETP (0.48) CETP
SCHEMBL12444137 0.79 CETP (0.53) CETP
SCHEMBL970291 0.79 CETP (0.55) CETP
SCHEMBL12445078 0.79 CETP (0.53) CETP
SCHEMBL973261 0.78 CETP (0.59) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2268644-B1 TRICYCLIC PYRIDINE DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PREPARATION BOEHRINGER INGELHEIM INT (DE) 2011-08-17 EP claimed