Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL2296008 | 0.97 | HSP90AA1 (0.33) | HSP90AA1NOS3NOS1NOS2 | |
| SCHEMBL1856675 | 0.84 | HSP90AA1 (0.35) | HSP90AA1NOS3NOS1NOS2 | |
| SCHEMBL310530 | 0.78 | — | — | |
| SCHEMBL20567997 | 0.78 | — | — | |
| SCHEMBL21031336 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL31064520 | 0.76 | HSP90AA1 (0.36) | HSP90AA1NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL23757961 | 0.76 | HSP90AA1 (0.36) | HSP90AA1NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL29720365 | 0.76 | HSP90AA1 (0.36) | HSP90AA1NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL23357683 | 0.76 | HSP90AA1 (0.36) | HSP90AA1NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL29236360 | 0.76 | HSP90AA1 (0.36) | HSP90AA1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107739371-A | A kind of Tetrahydrocarbazolesand small molecular organic compounds and its purposes in antibacterials are prepared and preparation method thereof | 华东师范大学 | 2018-02-27 | — | — | CN | claimed |
| CN-111032643-B | Quinolinone compounds | 詹森药业有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-11384075-B2 | Quinolinone compounds | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-12 | — | — | US | disclosed |
| US-20210139470-A1 | New Quinolinone Compounds | JOHNSON & JOHNSON (CHINA) INVESTMENT LTD. (CN) | 2021-05-13 | — | — | US | disclosed |
| CN-111032643-A | Quinolinone compounds | 詹森药业有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-107739371-A | A kind of Tetrahydrocarbazolesand small molecular organic compounds and its purposes in antibacterials are prepared and preparation method thereof | 华东师范大学 | 2018-02-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139470-A1 | New Quinolinone Compounds | FGFR1, FGFR2, FGFR3 | HSP90AA1 2894/4885NOS3 4696/4885NOS1 4505/4885 |
| US-11384075-B2 | Quinolinone compounds | FGFR1, FGFR2, FGFR3 | HSP90AA1 2428/4885NOS3 4706/4885NOS1 4534/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.