SCHEMBL23327477

SCHEMBL23327477

Brc1cccc2c1-c1ccccc1C21c2ccccc2C(c2ccccc2)(c2ccccc2)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 2/20 0.49
LMNA P02545 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPT P10636 1/20 0.42
OPRK1 P41145 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSP90AA1 P07900 1/20 0.36
CFTR P13569 1/20 0.36
GOPC Q9HD26 1/20 0.36
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
POLB P06746 1/20 0.33
AKR1C1 Q04828 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30805728 1.00 PDK2 (0.49) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL29352350 0.96 PDK2 (0.51) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL15550688 0.96 PDK2 (0.51) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL19760027 0.92 PDK2 (0.45) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL16810678 0.91 PDK2 (0.56) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL16858243 0.90 PDK2 (0.46) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL16810667 0.89 PDK2 (0.54) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL29603205 0.89 PDK2 (0.58) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL4195471 0.89 PDK2 (0.58) PDK2LMNAMEN1KMT2AKDM4E
SCHEMBL22125456 0.89 PDK2 (0.45) PDK2LMNAMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210147336-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME DOOSAN SOLUS CO., LTD. (KR) 2021-05-20 US disclosed
US-20210143327-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOOSAN SOLUS CO., LTD. (KR) 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210147336-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME OR10J3, ORAI2, OR51E2 PDK2 2458/4885LMNA 2313/4885MEN1 1924/4885
US-20210143327-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME OR10J3, ICOSLG, L1CAM PDK2 1288/4885LMNA 2751/4885MEN1 3394/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.