Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 18/20 | 0.61 |
| ▸ | PPARG | P37231 | 15/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2332479 | 1.00 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL2361274 | 1.00 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL6813813 | 0.86 | PPARA (0.76) | PPARAPPARGPPARD | |
| SCHEMBL5803154 | 0.84 | PPARG (0.52) | PPARAPPARGPPARD | |
| SCHEMBL3313236 | 0.84 | PPARG (0.58) | PPARAPPARGPPARD | |
| SCHEMBL4874828 | 0.84 | PPARG (0.58) | PPARAPPARG | |
| SCHEMBL6529677 | 0.84 | PPARA (0.53) | PPARAPPARGPPARD | |
| Hydrochloric Acid SCHEMBL5738405 | 0.83 | PPARG (0.57) | PPARAPPARG | |
| SCHEMBL27674855 | 0.83 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL13475126 | 0.82 | PPARG (0.69) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012177956-A1 | PPAR-SPARING COMPOUNDS FOR USE IN THE TREATMENT OF DIABETES AND OTHER METABOLIC DISEASES | METABOLIC SOLUTIONS DEVELOPMENT COMAPNY, LLC (US) | 2012-12-27 | — | — | WO | disclosed |
| WO-2011098801-A1 | INFLAMMATORY DISEASE TREATMENT | PULMAGEN THERAPEUTICS (INFLAMMATION) LIMITED (GB) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011098801-A1 | INFLAMMATORY DISEASE TREATMENT | PULMAGEN THERAPEUTICS (INFLAMMATION) LIMITED (GB) | 2011-08-18 | — | — | WO | disclosed |