SCHEMBL23328756

SCHEMBL23328756

N#Cc1ccc(N(c2ccc(C#N)cc2)c2ccc3oc4ccccc4c3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.47
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
MAPT P10636 4/20 0.44
NPC1 O15118 3/20 0.44
HPGD P15428 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
RAB9A P51151 2/20 0.44
AHR P35869 2/20 0.40
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
BCAT1 P54687 1/20 0.36
LMNA P02545 1/20 0.35
RORC P51449 1/20 0.34
TSHR P16473 1/20 0.34
MAOA P21397 2/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14313931 0.96 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL25544356 0.96 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL23328474 0.96 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL14295615 0.93 TNKS (0.48) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL14295621 0.92 TNKS (0.47) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL23328421 0.90 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL23328472 0.90 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL25543177 0.90 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL25544088 0.90 TNKS (0.50) TNKSKDM4EALDH1A1MAPTNPC1
SCHEMBL23328415 0.89 KDM4E (0.44) TNKSKDM4EALDH1A1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021085817-A2 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2021-05-06 WO disclosed