SCHEMBL23329035

SCHEMBL23329035

NC1CC(F)(c2ccc(Br)nc2F)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.31
MAOA P21397 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29740032 0.88 HRH4 (0.33)
SCHEMBL23329038 0.83
SCHEMBL23328842 0.82
Hydrochloric Acid SCHEMBL28949069 0.82
Hydrochloric Acid SCHEMBL28949067 0.82
SCHEMBL23300651 0.75
Trifluoroacetic Acid SCHEMBL29740096 0.73 HRH4 (0.33)
SCHEMBL31289640 0.69 EPHX2 (0.37) MAOB
SCHEMBL23300625 0.69 EPHX2 (0.37) MAOB
SCHEMBL23300626 0.69 CCNT1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230012600-A1 BRIDGED CYCLOFORMYLPYRIDINE DERIVATIVES AND USES THEREOF BROADENBIO CO., LTD. (CN) 2023-01-19 US disclosed
WO-2021083011-A1 BRIDGED CYCLOFORMYLPYRIDINE DERIVATIVE AND USE THEREOF 北京伯汇生物技术有限公司 2021-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230012600-A1 BRIDGED CYCLOFORMYLPYRIDINE DERIVATIVES AND USES THEREOF FGFR4, FGFR1, FGFR3 MAOB 2707/4885MAOA 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.