Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 13/20 | 0.40 |
| ▸ | CNR1 | P21554 | 6/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23305459 | 0.96 | CD38 (0.46) | CD38CNR2CNR1FAAH | |
| SCHEMBL23329181 | 0.89 | CD38 (0.43) | CD38CNR2CNR1 | |
| SCHEMBL24962688 | 0.89 | CD38 (0.43) | CD38CNR2CNR1 | |
| SCHEMBL23305211 | 0.82 | CD38 (0.53) | CD38 | |
| SCHEMBL23329200 | 0.82 | CD38 (0.54) | CD38 | |
| SCHEMBL23305076 | 0.81 | CD38 (0.45) | CD38 | |
| SCHEMBL23329197 | 0.80 | CD38 (0.51) | CD38 | |
| SCHEMBL23306488 | 0.80 | CD38 (0.54) | CD38 | |
| SCHEMBL23305001 | 0.80 | CD38 (0.58) | CD38 | |
| SCHEMBL23304645 | 0.80 | CD38 (0.44) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087087-A1 | N-CYCLOHEXYL-5-(THIAZOL-5-YL)-1H-INDOLE-7-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS CD38 INHIBITORS FOR INCREASING NAD+ AND FOR THE TREATMENT OF E.G. MUSCULAR DISORDERS | MITOBRIDGE INC. (US) | 2021-05-06 | — | — | WO | disclosed |