Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | AOC2 | O75106 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2413925 | 0.87 | PLCG1 (0.59) | PLCG1CTDSP1POLBMAPK1HTT | |
| SCHEMBL22289434 | 0.84 | PLCG1 (0.55) | PLCG1CTDSP1POLBMAPK1HTT | |
| SCHEMBL14538238 | 0.83 | CRBN (0.52) | CNR2MAPK1KDM1ACRBN | |
| SCHEMBL28160358 | 0.82 | PLCG1 (0.53) | PLCG1CNR2CTDSP1POLBMAPK1 | |
| SCHEMBL23329484 | 0.81 | PLCG1 (0.44) | PLCG1CTDSP1POLBMAPK1HTT | |
| SCHEMBL1938684 | 0.79 | PLCG1 (0.50) | PLCG1CNR2CTDSP1POLBMAPK1 | |
| SCHEMBL17123616 | 0.79 | PLCG1 (0.50) | PLCG1CTDSP1POLBMAPK1HTT | |
| SCHEMBL23329648 | 0.79 | TDP1 (0.56) | CNR2POLBHTTCHRM1CHRM3 | |
| SCHEMBL5212189 | 0.79 | MAPK1 (0.41) | PLCG1CNR2SLC6A4MAPK1HTT | |
| SCHEMBL19420464 | 0.79 | CNR2 (0.39) | CNR2SLC6A4KDM1AEP300CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083209-A1 | SSAO INHIBITORS AND USE THEREOF | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2021-05-06 | — | — | WO | disclosed |