Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 19/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23305211 | 0.81 | CD38 (0.53) | CD38 | |
| SCHEMBL23329393 | 0.80 | CD38 (0.47) | CD38 | |
| SCHEMBL23329183 | 0.78 | CD38 (0.40) | CD38 | |
| SCHEMBL23304684 | 0.77 | CD38 (0.74) | CD38 | |
| SCHEMBL23329533 | 0.74 | CD38 (0.73) | CD38 | |
| SCHEMBL23329531 | 0.74 | HDAC4 (0.42) | CD38 | |
| SCHEMBL23329198 | 0.73 | CD38 (0.38) | CD38 | |
| SCHEMBL23329449 | 0.72 | CD38 (0.58) | CD38 | |
| SCHEMBL23329849 | 0.71 | CD38 (0.64) | CD38 | |
| SCHEMBL23329886 | 0.70 | CD38 (0.57) | CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087087-A1 | N-CYCLOHEXYL-5-(THIAZOL-5-YL)-1H-INDOLE-7-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS CD38 INHIBITORS FOR INCREASING NAD+ AND FOR THE TREATMENT OF E.G. MUSCULAR DISORDERS | MITOBRIDGE INC. (US) | 2021-05-06 | — | — | WO | disclosed |