Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 5/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23331026 | 0.82 | — | — | |
| SCHEMBL23331291 | 0.82 | TLR7 (0.32) | — | |
| SCHEMBL23330631 | 0.79 | MAPT (0.37) | PARP15PARP10TNKS2PARP2KDM4E | |
| SCHEMBL23331286 | 0.78 | JAK2 (0.31) | — | |
| SCHEMBL23330885 | 0.76 | — | — | |
| SCHEMBL21287491 | 0.76 | HRH4 (0.37) | — | |
| SCHEMBL23330582 | 0.74 | ABCB1 (0.39) | KDM4EALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL23331289 | 0.74 | CGAS (0.32) | — | |
| SCHEMBL23330588 | 0.74 | MAPK14 (0.41) | MAPTLMNAHTTSMN1; SMN2BRD4 | |
| SCHEMBL23331095 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083380-A1 | EED INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海科技大学 | 2021-05-06 | — | — | WO | disclosed |