Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23304031 | 0.92 | BTK (0.43) | BTKLCK | |
| SCHEMBL23303757 | 0.92 | BTK (0.44) | BTKLCK | |
| SCHEMBL23303684 | 0.89 | BTK (0.40) | BTKLCK | |
| SCHEMBL23303764 | 0.88 | BTK (0.41) | BTKLCK | |
| SCHEMBL23304108 | 0.88 | BTK (0.41) | BTKLCK | |
| SCHEMBL23303697 | 0.88 | BTK (0.41) | BTKLCK | |
| SCHEMBL23304084 | 0.87 | BTK (0.40) | BTKLCK | |
| SCHEMBL23336744 | 0.87 | BTK (0.48) | BTKLCK | |
| SCHEMBL29976934 | 0.87 | BTK (0.48) | BTKLCK | |
| SCHEMBL23304215 | 0.87 | BTK (0.39) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087112-A1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |