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SCHEMBL23337103

SCHEMBL23337103

CC(C)c1cccc(C(C)C)c1N1/C(=C\C=C2C(=O)c3cc4ccccc4cc3C2=O)N(c2c(-c3cc(F)cc(F)c3)cccc2-c2cc(F)cc(F)c2)c2nc3ccccc3nc21

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 4/20 0.34
▸ NR1H2 P55055 1/20 0.34
▸ NR1H3 Q13133 1/20 0.34
▸ ANPEP P15144 4/20 0.31
▸ BCL2 P10415 2/20 0.31
▸ MCL1 Q07820 2/20 0.31
▸ BCL2A1 Q16548 2/20 0.31
▸ MET P08581 1/20 0.31
▸ BCL2L1 Q07817 1/20 0.30
▸ PIK3C2B O00750 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23337585 0.94 DPP4 (0.31) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337148 0.90 ANPEP (0.32) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337591 0.89 DPP4 (0.39) DPP4NR1H2NR1H3ANPEPBCL2
SCHEMBL23338729 0.89 DPP4 (0.34) DPP4NR1H2NR1H3ANPEPBCL2
SCHEMBL23338730 0.87 DPP4 (0.31) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337551 0.86 ANPEP (0.34) DPP4NR1H2NR1H3ANPEPBCL2
SCHEMBL23338743 0.86 DPP4 (0.32) DPP4NR1H2NR1H3ANPEP
SCHEMBL23338666 0.86 DPP4 (0.36) DPP4NR1H2NR1H3ANPEP
SCHEMBL23367722 0.84 DPP4 (0.33) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337546 0.84 DPP4 (0.42) DPP4NR1H2NR1H3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 — — US disclosed