SCHEMBL23337157

SCHEMBL23337157

Cc1cc(-c2ccc(Cl)cc2)c(N2/C(=C/C=C3C(=O)c4cc5ccccc5cc4C3=O)N(c3c(C(C)C)cccc3C(C)C)c3nc4ccccc4nc32)c(-c2ccc(Cl)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
TDP1 Q9NUW8 3/20 0.35
MAPT P10636 3/20 0.35
HPGD P15428 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TRPV1 Q8NER1 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
GAA P10253 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
DPP4 P27487 2/20 0.31
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
ANPEP P15144 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23337588 0.93 DPP4 (0.31) TRPV1DPP4NR1H2NR1H3ANPEP
SCHEMBL23367722 0.93 DPP4 (0.33) ALDH1A1KDM4ETDP1MAPTHPGD
SCHEMBL23338731 0.91 ANPEP (0.32) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337551 0.91 ANPEP (0.34) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337147 0.90 DPP4 (0.31) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337159 0.90 DPP4 (0.31) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337587 0.89 KDM4E (0.31) KDM4EHPGDTRPV1DPP4ANPEP
SCHEMBL23337900 0.89 MEN1 (0.33) MEN1KMT2A
SCHEMBL23337586 0.89 DPP4 (0.31) DPP4NR1H2NR1H3ANPEP
SCHEMBL23337585 0.88 DPP4 (0.31) DPP4NR1H2NR1H3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3823054-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM Corporation (JP) 2021-05-19 EP disclosed
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 US disclosed