SCHEMBL23339093

SCHEMBL23339093

c1ccc(-c2nc(-c3ccc4c(c3)oc3cccc(-c5ccccc5)c34)nc(-n3c4ccccc4c4ccc5oc6ccccc6c5c43)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.34
HCRTR1 O43613 1/20 0.32
MAPK14 Q16539 1/20 0.32
MAPT P10636 5/20 0.31
KDM4E B2RXH2 3/20 0.31
TSHR P16473 3/20 0.31
MAPK1 P28482 2/20 0.31
HSD17B10 Q99714 2/20 0.31
DUSP3 P51452 1/20 0.31
LMNA P02545 1/20 0.31
ALDH1A1 P00352 3/20 0.30
HPGD P15428 2/20 0.30
POLB P06746 1/20 0.30
TP53 P04637 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
ATM Q13315 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23339583 0.99 BACE1 (0.34) BACE1HCRTR1MAPK14MAPTKDM4E
SCHEMBL23339754 0.98 HCRTR1 (0.33) BACE1HCRTR1MAPK14MAPT
SCHEMBL23339760 0.96 HCRTR1 (0.33) BACE1HCRTR1MAPK14ATM
SCHEMBL23339763 0.96 BACE1 (0.33) BACE1HCRTR1MAPK14
SCHEMBL24702034 0.95 BACE1 (0.34) BACE1HCRTR1MAPK14MAPTKDM4E
SCHEMBL24883072 0.93 BACE1 (0.33) BACE1HCRTR1
SCHEMBL24883070 0.93 BACE1 (0.33) BACE1HCRTR1MAPK14MAPTKDM4E
SCHEMBL23339098 0.93 BACE1 (0.36) BACE1HCRTR1MAPTKDM4ETSHR
SCHEMBL23339094 0.92 BACE1 (0.33) BACE1HCRTR1MAPK14MAPTKDM4E
SCHEMBL17524725 0.92 DUSP3 (0.33) BACE1MAPK14MAPTKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021085969-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2021-05-06 WO disclosed