SCHEMBL23339337

SCHEMBL23339337

c1ccc(-c2nc(-c3ccc(-n4c5ccccc5c5c6c(ccc54)oc4ccccc46)cc3)nc(-c3ccc4c(c3)oc3cccc(-c5ccccc5)c34)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.34
PTGER4 P35408 1/20 0.32
HCRTR1 O43613 1/20 0.32
KDM4E B2RXH2 3/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPT P10636 2/20 0.30
SIRT2 Q8IXJ6 1/20 0.30
SIRT1 Q96EB6 1/20 0.30
TSHR P16473 2/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALDH1A1 P00352 2/20 0.30
HPGD P15428 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25965007 0.96 KDM4E (0.35) BACE1PTGER4HCRTR1KDM4EATM
SCHEMBL23339339 0.95 BACE1 (0.33) BACE1HCRTR1KDM4EATML3MBTL1
SCHEMBL25965004 0.93 KDM4E (0.34) BACE1HCRTR1KDM4EATML3MBTL1
SCHEMBL27324582 0.93 BACE1 (0.34) BACE1HCRTR1KDM4EATML3MBTL1
SCHEMBL24078212 0.92 KDM4E (0.35) BACE1KDM4EATML3MBTL1
SCHEMBL24078753 0.92 KDM4E (0.33) BACE1KDM4EATML3MBTL1
SCHEMBL27333142 0.92 PTGER4 (0.36) BACE1PTGER4HCRTR1KDM4EATM
SCHEMBL23913847 0.92 KDM4E (0.36) BACE1PTGER4HCRTR1KDM4EATM
SCHEMBL23299592 0.92 KDM4E (0.38) BACE1PTGER4HCRTR1KDM4EATM
SCHEMBL23339104 0.91 PRKDC (0.35) BACE1PTGER4HCRTR1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021085969-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2021-05-06 WO disclosed