Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CCR1 | P32246 | 1/20 | 0.61 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.61 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450988 | 0.83 | FERMT2 (0.63) | CYP1A2CCR1NR4A2FERMT2ALDH1A1 | |
| SCHEMBL27953778 | 0.82 | CYP1A2 (0.59) | CYP1A2CCR1NR4A2FERMT2ALDH1A1 | |
| SCHEMBL23904645 | 0.82 | NR4A2 (0.70) | CYP1A2CCR1NR4A2FERMT2ALDH1A1 | |
| SCHEMBL23904647 | 0.82 | NR4A2 (0.57) | CYP1A2CCR1NR4A2FERMT2ALDH1A1 | |
| SCHEMBL23340249 | 0.82 | NR4A2 (0.57) | CYP1A2CCR1NR4A2FERMT2MAPT | |
| SCHEMBL23904644 | 0.81 | FERMT2 (0.62) | CYP1A2CCR1NR4A2FERMT2ALDH1A1 | |
| SCHEMBL28270221 | 0.81 | HTT (0.81) | FERMT2ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL23883137 | 0.79 | NR4A2 (0.54) | CYP1A2CCR1NR4A2FERMT2LMNA | |
| SCHEMBL23340476 | 0.79 | NR4A2 (0.54) | CYP1A2CCR1NR4A2FERMT2LMNA | |
| SCHEMBL7656126 | 0.79 | MAPT (0.63) | CYP1A2CCR1NR4A2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022696-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-01-26 | — | — | US | disclosed |
| WO-2021087077-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230022696-A1 | SMALL MOLECULE INHIBITORS OF AUTOPHAGY AND HISTONE DEACTYLASES AND USES THEREOF | HDAC5, HDAC4, HDAC7 | CYP1A2 3113/4885CCR1 4704/4885NR4A2 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.