Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360781 | 1.00 | CNR2 (0.50) | CNR2TSHRKEAP1DPP4MMP2 | |
| SCHEMBL233440 | 1.00 | CNR2 (0.50) | CNR2TSHRKEAP1DPP4MMP2 | |
| Ammonia Solution, Strong SCHEMBL28234808 | 0.98 | CNR2 (0.49) | CNR2TSHRKEAP1DPP4MMP2 | |
| SCHEMBL27859676 | 0.98 | CNR2 (0.49) | CNR2TSHRKEAP1DPP4MMP2 | |
| SCHEMBL27859674 | 0.98 | CNR2 (0.49) | CNR2TSHRKEAP1DPP4MMP2 | |
| Nitrous Acid SCHEMBL27625772 | 0.92 | MME (0.46) | CNR2TSHRKEAP1DPP4MMP2 | |
| SCHEMBL5962191 | 0.89 | S1PR2 (0.54) | CNR2TSHRMMEMEN1HTT | |
| Trifluoroacetic Acid SCHEMBL8142317 | 0.89 | CPA1 (0.49) | CNR2TSHRKEAP1CYP1A2MME | |
| SCHEMBL7761730 | 0.89 | S1PR2 (0.54) | CNR2TSHRMMEMEN1HTT | |
| SCHEMBL8688130 | 0.89 | S1PR2 (0.54) | CNR2TSHRMMEMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382699-B | Methods of producing polyhydroxyalkanoates using 2-hydroxyisocaproate-CoA transferase | 韩国科学技术院 | 2024-04-05 | — | — | CN | claimed |
| CN-117339390-A | Synergistic extraction system and extraction process for extracting and separating boron isotopes | 中国科学院过程工程研究所 | 2024-01-05 | — | — | CN | claimed |
| WO-2023198025-A1 | SYNTHESIS METHOD AND SYNTHESIS DEVICE FOR ORGANIC NITROGEN-CONTAINING COMPOUND | 中山大学 | 2023-10-19 | — | — | WO | claimed |
| CN-115851641-A | Fusion enzyme for efficiently producing (R) -2-hydroxy-4-phenylbutyric ethyl butyrate and application thereof | 浙江工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-115820622-A | Double-enzyme self-assembly compound and application of compound in synthesizing (R) -2-hydroxy-4-phenylbutyrate | 浙江工业大学 | 2023-03-21 | — | — | CN | claimed |
| EP-3543225-B1 | METHOD FOR PREPARING LISINOPRIL INTERMEDIATE | ZHEJIANG HUAHAI PHARM CO LTD (CN) | 2023-01-04 | — | — | EP | claimed |
| CN-110903177-B | Method for preparing levo muscone | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| CN-114487076-A | Method for analyzing enantiomer structures of R, S-mandelic acid and derivatives thereof | 宁波大学 | 2022-05-13 | — | — | CN | claimed |
| CN-111218441-B | Magnetic immobilized yeast cell and application thereof in preparation of (R) -2-hydroxy-4-phenylbutyrate ethyl ester | 浙江工业大学 | 2022-03-18 | — | — | CN | claimed |
| CN-106866402-B | Preparation method of (R) -2-hydroxy-4-phenylbutyric acid | 泰州市产品质量监督检验所 | 2021-08-31 | — | — | CN | claimed |
| US-5098841-A | Reduction of 2-oxo-4-phenylbutyric acid with the enzyme D lactate dehydrogenase from staphylococcus or from bovine heart | CIBA-GEIGY CORPORATION (US) | 1992-03-24 | — | — | US | claimed |
| US-5077217-A | Using enzymes in aqueous solutions | SEPRACOR, INC. (US) | 1991-12-31 | — | — | US | claimed |
| US-5057427-A | Enzymatic hydrolysis | SEPRACOR, INC. (US) | 1991-10-15 | — | — | US | claimed |
| EP-0423133-A1 | ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS. | SEPRACOR INC (US) | 1991-04-24 | — | — | EP | claimed |
| EP-0394448-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE 2-HYDROXY-4-PHENYLBUTYRIC ACIDS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1990-10-31 | — | — | EP | claimed |
| US-4904822-A | Process for the optical resolution of (+)-2-hydroxy-4-phenylbutanoic acid | KURARAY CO., LTD. (JP) | 1990-02-27 | — | — | US | claimed |
| WO-1989009765-A1 | ENZYMATIC RESOLUTION SYSTEMS AND COMPOUNDS USEFUL IN THE SYSTEMS AND THEIR REPARATIONS | SEPRACOR, INC. (US) | 1989-10-19 | — | — | WO | claimed |
| EP-0329156-A1 | Process for the optical resolution of (+-)-2-hydroxy-4-phenylbutanoic acid | KURARAY CO., LTD. (JP) | 1989-08-23 | — | — | EP | claimed |
| US-4837354-A | Process for making and isolating (R)-2-hydroxy-4-phenylbutyric acid and esters | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-06-06 | — | — | US | claimed |
| EP-0280285-A2 | Process for making and isolating (R)-2-hydroxy 4-phenylbutyric acid and esters | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-31 | — | — | EP | claimed |