Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 16/20 | 0.44 |
| ▸ | CDK9 | P50750 | 15/20 | 0.44 |
| ▸ | CDK7 | P50613 | 3/20 | 0.39 |
| ▸ | CCNH | P51946 | 3/20 | 0.39 |
| ▸ | MNAT1 | P51948 | 3/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | CLK3 | P49761 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23351756 | 0.91 | CDK2 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23351993 | 0.91 | CDK2 (0.46) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL26340656 | 0.91 | CDK2 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23352021 | 0.90 | CDK2 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23352092 | 0.90 | CDK2 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL26340651 | 0.89 | CDK2 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23381945 | 0.88 | CDK2 (0.41) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23352111 | 0.88 | CDK2 (0.42) | CDK2CDK9CDK7DYRK3CCNT1 | |
| SCHEMBL21481510 | 0.87 | CDK2 (0.43) | CDK2CDK9CDK7CCNHMNAT1 | |
| SCHEMBL23352091 | 0.87 | CDK7 (0.41) | CDK2CDK9CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11858937-B2 | Substituted pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors | QURIENT CO., LTD. (KR) | 2024-01-02 | — | — | US | disclosed |
| US-20210139483-A1 | PHARMACEUTICALLY ACTIVE PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES | LEAD DISCOVERY CENTER GMBH (DE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11858937-B2 | Substituted pyrazolo[1,5-a]pyrimidines and pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors | CDKL5, CDK15, CDK5 | CDK2 9/4885CDK9 7/4885CDK7 10/4885 |
| US-20210139483-A1 | PHARMACEUTICALLY ACTIVE PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES | IL5, THPO, TYMP | CDK2 171/4885CDK9 237/4885CDK7 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.