Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 18/20 | 0.72 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16112798 | 1.00 | OGA (0.72) | OGAACKR3HTTSMN1; SMN2OPRK1 | |
| SCHEMBL16112513 | 0.89 | OGA (0.67) | OGAACKR3HTTSMN1; SMN2 | |
| SCHEMBL16113559 | 0.88 | OGA (0.80) | OGAACKR3HTTSMN1; SMN2 | |
| SCHEMBL20281706 | 0.86 | OGA (0.75) | OGAOPRK1 | |
| SCHEMBL20281782 | 0.85 | OGA (0.63) | OGAACKR3OPRK1 | |
| SCHEMBL21359519 | 0.85 | OGA (0.76) | OGAACKR3OPRK1 | |
| SCHEMBL21369551 | 0.85 | OGA (0.76) | OGAACKR3OPRK1 | |
| SCHEMBL27008676 | 0.84 | OGA (1.00) | OGAOPRK1 | |
| SCHEMBL22004826 | 0.83 | OGA (0.67) | OGASMN1; SMN2OPRK1 | |
| SCHEMBL22005091 | 0.81 | OGA (0.55) | OGAACKR3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077323-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| EP-4076654-A1 | OGA INHIBITOR COMPOUNDS | Janssen Pharmaceutica NV (BE) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021123291-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021123297-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021123294-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021110656-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-10 | — | — | WO | disclosed |
| WO-2021094312-A1 | PYRROLIDINE AND BICYCLOHETEROARYL CONTAINING OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-05-20 | — | — | WO | disclosed |