Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23364342 | 1.00 | KDM4E (0.38) | KDM4ECYP3A4MAPK1CYP1A2CYP2C9 | |
| SCHEMBL23364247 | 1.00 | KDM4E (0.38) | KDM4ECYP3A4MAPK1CYP1A2CYP2C9 | |
| SCHEMBL24910706 | 0.93 | KDM4E (0.40) | KDM4ECYP3A4MAPK1CYP1A2CYP2C9 | |
| SCHEMBL23364264 | 0.91 | KDM4E (0.41) | KDM4ECYP3A4CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL24910673 | 0.91 | KDM4E (0.41) | KDM4ECYP3A4CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL23364299 | 0.91 | KDM4E (0.41) | KDM4ECYP3A4CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL24911755 | 0.85 | HCRTR1 (0.38) | KDM4ECYP3A4CYP1A2ALDH1A1USP2 | |
| SCHEMBL23364316 | 0.78 | CYP11B1 (0.38) | KDM4ECYP3A4MAPK1CYP1A2CYP2C9 | |
| SCHEMBL23364303 | 0.78 | CYP11B1 (0.38) | KDM4ECYP3A4MAPK1CYP1A2CYP2C9 | |
| SCHEMBL23364277 | 0.78 | KDM4E (0.37) | KDM4ECYP3A4MAPK1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021097075-A1 | SUBSTITUTED ISOINDOLONYL 2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA, INC. (US) | 2021-05-20 | — | — | WO | disclosed |