Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXK | P42681 | 16/20 | 0.72 |
| ▸ | ITK | Q08881 | 10/20 | 0.72 |
| ▸ | JAK3 | P52333 | 15/20 | 0.71 |
| ▸ | BTK | Q06187 | 13/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366066 | 0.92 | TXK (0.81) | TXKITKJAK3BTK | |
| SCHEMBL20161845 | 0.86 | JAK3 (0.78) | TXKITKJAK3BTK | |
| SCHEMBL23365927 | 0.86 | TXK (0.77) | TXKITKJAK3BTK | |
| SCHEMBL23366085 | 0.85 | TXK (1.00) | TXKITKJAK3BTK | |
| SCHEMBL24467221 | 0.85 | TXK (1.00) | TXKITKJAK3BTK | |
| SCHEMBL23366081 | 0.84 | TXK (0.82) | TXKITKJAK3BTK | |
| SCHEMBL23366083 | 0.84 | JAK3 (0.81) | TXKITKJAK3BTK | |
| Soquelitinib SCHEMBL24467290 | 0.84 | TXK (1.00) | TXKITKJAK3BTK | |
| Soquelitinib SCHEMBL20161546 | 0.84 | TXK (1.00) | TXKITKJAK3BTK | |
| Soquelitinib SCHEMBL20161402 | 0.84 | TXK (1.00) | TXKITKJAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008314-B2 | Compounds and methods for modulating interleukin-2-inducible t-cell kinase | CORVUS PHARMACEUTICALS, INC. (US) | 2021-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008314-B2 | Compounds and methods for modulating interleukin-2-inducible t-cell kinase | IL2, NFATC1, IL2RA | TXK 201/4885ITK 282/4885JAK3 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.