SCHEMBL233670

SCHEMBL233670

CCCCNCC(N[SiH3])(NCCCC)NCCCC

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ADH7 P40394 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL233759 0.83
SCHEMBL233671 0.76 TSHR (0.35) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL235200 0.70 TSHR (0.33) TSHRADH1BADH1CADH1AADH7
SCHEMBL10198685 0.67 TSHR (0.52) TSHRALDH1A1POLBSMN1; SMN2L3MBTL1
SCHEMBL3286955 0.66 TSHR (0.50) TSHRALDH1A1POLBSMN1; SMN2L3MBTL1
SCHEMBL2608049 0.66 TSHR (0.50) TSHRALDH1A1POLBSMN1; SMN2L3MBTL1
SCHEMBL27946380 0.65 TSHR (0.79) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL2532 0.65
SCHEMBL1536124 0.64 TSHR (0.41) TSHRALDH1A1ADH1BADH1CADH1A
SCHEMBL21553357 0.64 TSHR (0.48) TSHRALDH1A1POLBSMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360190-B1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO LTD (JP) 2015-10-14 EP disclosed
US-8426537-B2 Solid catalyst component and catalyst for polymerization of olefins, and process for production of olefin polymers using same TOHO TITANIUM CO., LTD. (JP) 2013-04-23 US disclosed
US-20120004378-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME TOHO TITANIUM CO., LTD (JP) 2012-01-05 US disclosed
EP-2360190-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFINS, AND PROCESS FOR PRODUCTION OF OLEFIN POLYMERS USING SAME Toho Titanium CO., LTD. (JP) 2011-08-24 EP disclosed