SCHEMBL23367676

SCHEMBL23367676

CCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(NC)cc4)CC3)c(CC)cc2C)[nH]1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12686848 0.90 FASN (0.58) FASN
SCHEMBL12489346 0.88 FASN (0.74) FASN
SCHEMBL23367763 0.83 FASN (0.59) FASN
SCHEMBL12686907 0.83 FASN (0.57) FASN
SCHEMBL30280950 0.82 FASN (0.56) FASN
SCHEMBL12489192 0.82 FASN (0.56) FASN
SCHEMBL12489520 0.81 FASN (0.73) FASN
SCHEMBL12488043 0.81 FASN (0.73) FASN
SCHEMBL30281097 0.81 FASN (0.73) FASN
SCHEMBL30280990 0.81 FASN (0.56) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190108-B1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS SAGIMET BIOSCIENCES INC (US) 2021-05-19 EP disclosed