SCHEMBL23367755

SCHEMBL23367755

Cc1ccc(C2(F)CCN(C(=O)c3ccc(C)c(NC(=O)NC4CCCOC4)c3)CC2)cc1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12687003 0.95 FASN (0.83) FASN
SCHEMBL23367723 0.95 FASN (0.83) FASN
SCHEMBL12687035 0.95 FASN (0.83) FASN
SCHEMBL12686821 0.94 FASN (0.81) FASN
SCHEMBL13455027 0.91 FASN (0.86) FASN
SCHEMBL12489331 0.91 FASN (1.00) FASN
SCHEMBL20142307 0.91 FASN (1.00) FASN
SCHEMBL12686823 0.88 FASN (0.81) FASN
SCHEMBL12686969 0.87 FASN (0.81) FASN
SCHEMBL13454988 0.86 FASN (0.85) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3190108-B1 HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS SAGIMET BIOSCIENCES INC (US) 2021-05-19 EP disclosed