Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 10/20 | 0.35 |
| ▸ | SGPL1 | O95470 | 10/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23368752 | 0.87 | S1PR1 (0.45) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368838 | 0.85 | S1PR1 (0.42) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368942 | 0.85 | S1PR1 (0.47) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368844 | 0.84 | S1PR1 (0.47) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368812 | 0.82 | SGPL1 (0.41) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368955 | 0.82 | S1PR1 (0.45) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23369055 | 0.81 | S1PR1 (0.38) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368602 | 0.80 | S1PR1 (0.49) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368745 | 0.80 | S1PR1 (0.49) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL23368815 | 0.80 | S1PR1 (0.49) | S1PR1SGPL1CYP1A2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3183242-B1 | SUBSTITUTED BICYCLIC COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2021-05-19 | — | — | EP | disclosed |