SCHEMBL23370352

SCHEMBL23370352

c1ccc(-c2cc(-n3c4ccccc4c4cc(-c5ccccc5)c5c6ccccc6n(-c6ccccc6)c5c43)nc(-c3ccccc3)n2)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
MAPK1 P28482 3/20 0.40
TSHR P16473 2/20 0.40
HSD17B10 Q99714 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HPGD P15428 4/20 0.39
KDM4E B2RXH2 4/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
ALDH1A1 P00352 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
NTSR1 P30989 1/20 0.33
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
GRM5 P41594 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21017467 0.91 MAPT (0.40) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL16353142 0.89 KDM4E (0.37) MAPTMAPK1TSHRHSD17B10HPGD
SCHEMBL15450034 0.88 MAPT (0.45) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL26421155 0.88 KDM4E (0.36) MAPTMAPK1HPGDKDM4EL3MBTL1
SCHEMBL21017476 0.88 MAPT (0.41) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL12131933 0.87 KDM4E (0.41) MAPTMAPK1HSD17B10HPGDKDM4E
SCHEMBL17245352 0.87 MAPT (0.46) MAPTMAPK1TSHRHSD17B10NPSR1
SCHEMBL22852215 0.86 KDM4E (0.41) MAPTMAPK1HSD17B10KDM4EL3MBTL1
SCHEMBL26421335 0.86 KDM4E (0.41) MAPTHSD17B10HPGDKDM4EL3MBTL1
SCHEMBL27050604 0.86 KDM4E (0.41) MAPTMAPK1HSD17B10KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 MAPT 4215/4885MAPK1 2036/4885TSHR 2393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.