SCHEMBL23370643

SCHEMBL23370643

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc(-c5ccncc5)c4)cc3)n2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.60
SMN1; SMN2 Q16637 4/20 0.56
MAPT P10636 4/20 0.56
NPC1 O15118 1/20 0.56
NFKB1 P19838 1/20 0.56
RAB9A P51151 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
HSD17B10 Q99714 1/20 0.56
MAPK13 O15264 2/20 0.49
MAPK12 P53778 2/20 0.49
MAPK11 Q15759 2/20 0.49
MAPK14 Q16539 2/20 0.49
GCGR P47871 1/20 0.49
MKNK1 Q9BUB5 1/20 0.49
ALDH1A1 P00352 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HPGD P15428 2/20 0.48
PIK3CA P42336 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25768874 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL25768876 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL17720922 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL18327496 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL18134340 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL25768873 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL18327485 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL20780352 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL21982128 0.98 NOTUM (0.58) NOTUMSMN1; SMN2MAPTNPC1NFKB1
SCHEMBL21481328 0.96 NOTUM (0.56) NOTUMSMN1; SMN2MAPTNPC1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME TORAY INDUSTRIES, INC. (JP) 2021-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210151683-A1 LIGHT-EMITTING ELEMENT, AND DISPLAY, ILLUMINATOR, AND SENSOR EACH INCLUDING SAME CBR3, INTS9, CBR1 NOTUM 3333/4885SMN1; SMN2 3469/4885MAPT 4215/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.