Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | PDE5A | O76074 | 17/20 | 0.62 |
| ▸ | PDE6C | P51160 | 3/20 | 0.62 |
| ▸ | PDE1A | P54750 | 2/20 | 0.62 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.62 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.59 |
| ▸ | PDE2A | O00408 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.59 |
| ▸ | PDE6D | O43924 | 1/20 | 0.59 |
| ▸ | PDE8A | O60658 | 1/20 | 0.59 |
| ▸ | PDE9A | O76083 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25925219 | 0.91 | PDE5A (0.62) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL23370650 | 0.89 | PDE5A (0.66) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL19942814 | 0.88 | PDE5A (0.70) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL23370752 | 0.88 | KMT2A (0.57) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL24893800 | 0.86 | KMT2A (0.73) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL29602364 | 0.84 | PDE5A (0.78) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL23361674 | 0.84 | PDE5A (0.78) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL24199882 | 0.84 | PDE5A (0.71) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL24221333 | 0.83 | PDE5A (0.62) | KMT2APDE5APDE6CPDE1APDE1B | |
| SCHEMBL23370678 | 0.82 | PDE5A (0.56) | KMT2APDE5APDE6CPDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021094830-A2 | NITROGEN OXIDE-DONATING PDE-5 AND/OR PDE-6 INHIBITOR COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2021-05-20 | — | — | WO | disclosed |